Comprehensive STD and STI screening options are available at convenient South Dakota locations, providing private, FDA-approved testing with quick results and compassionate care.
Our team is standing by to answer your questions and schedule your confidential STD testing appointment today.
Comprehensive STD and STI screening options are available at convenient South Dakota locations, providing private, FDA-approved testing with quick results and compassionate care.

Our 10-Panel includes HIV 1&2, Syphilis, Gonorrhea, Chlamydia, Hepatitis A/B/C, and Herpes 1&2. It’s ideal for full sexual health checkups and peace of mind. All tests are FDA-approved and available at all 30 South Dakota locations with consistent quality statewide.
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Choose targeted testing for specific concerns like HIV, Herpes, Chlamydia, Gonorrhea, Syphilis, or Hepatitis. Individual tests are cost-effective, deliver quick results, and can be ordered by phone from anywhere in South Dakota for convenient, private screening.
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We offer 4th generation antibody testing and FDA-approved HIV RNA Early Detection testing for the earliest possible detection (10-12 days post-exposure). Laboratory-based methods ensure accuracy and confidential counseling, available across partner labs in South Dakota.
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Type-specific IgG blood testing distinguishes HSV-1 and HSV-2. This accurate testing is useful for asymptomatic individuals and those with symptoms. Results include clinical interpretation and are available in Sioux Falls, Rapid City, Brookings, and rural areas across South Dakota.
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Chlamydia and gonorrhea are common bacterial STIs. We use simple urine-based testing for comfortable, accurate screening. Quick results and easy treatment referrals are available across South Dakota, where routine screening prevents serious complications.
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Our comprehensive hepatitis panel includes testing for Hepatitis A, B, and C via blood tests. Early detection protects liver health and is important for high-risk groups. Hepatitis testing is included in many panels and accessible at all South Dakota testing centers.
Learn more →Call our South Dakota team for a confidential consultation. Same-day appointments available statewide with knowledgeable staff who can order tests by phone for privacy and quick access to care.
Same-day appointments available statewide
📞 Call Now for Confidential TestingRegular STD testing is an essential part of preventive health care for sexually active people in South Dakota. Many sexually transmitted infections are asymptomatic, so testing is the only reliable way to know your status. The Centers for Disease Control and Prevention recommends routine screening for chlamydia, gonorrhea, HIV, and syphilis for at-risk groups. Young adults under 25 and people with new or multiple partners are higher risk and should test regularly. South Dakota’s health departments have noted regional increases in reported chlamydia and gonorrhea, mirroring Midwest trends, which underscores the importance of routine screening. Local universities such as South Dakota State University in Brookings and the University of South Dakota in Vermillion serve student populations where convenient, confidential testing is especially valuable. Early detection allows prompt treatment, reduces complications, and helps prevent onward transmission. Our South Dakota services support both urban centers like Sioux Falls and Rapid City and rural communities with private, FDA-approved testing, quick turnaround, and supportive counseling to reduce stigma and normalize sexual health care.